Fig. 6. GBP5 knockdown inhibits glioblastoma growth and invasion in mice.
A H&E staining of GSC206-shGBP5 and GSC206-shGFP (control) brain sections. B IHC staining of GBP5, p-Src, p-ERK1/2, and MMP3 in GSC206-shGBP5 and GSC206-shGFP tumors. C IHC staining of Ki67 and Caspase 3 in GSC206-shGBP5 and GSC-shGFP tumors. **p < 0.01; ***p < 0.001. n = 4. D Effect of GBP5 knockdown in the survival time of mice bearing tumor by survival studies. n = 6. p = 0.0057.