Figure 3.
Estrogen treatment in male LR/Stat3Δ/Δ mice reduced tumor burden. (a) Representative photomicrographs of the whole slide images of lung H&E stained sections (scale bar = 3 mm) and (b) tumor/lung area percentage (n = 3–4). (c) Lung surface tumor number (n = 9–17). (d) Representative photomicrographs of Ki-67 stained sections (n = 3–4) (scale bar = 200 μm), and (e) proliferative rate presented as percentage of Ki-67-positive cells. Data represent mean ± SEM; ****P < 0.0001, **P < 0.01, *P < 0.05, experimental replicate #3.