Table 1.
Classification of disaccharide phosphorylases.
| Mechanism | Family | Linkage | Donor | Acceptor | Product |
|---|---|---|---|---|---|
| Retaining (IR) | GT4 | α,α-(1 → 1) | α-D-Glc-1-P | D-Glc | Trehalose |
| Retaining (DD) | GH13 | α1→β2 | α-D-Glc-1-P | D-Fru | Sucrose |
| α-(1 → 2) | α-D-Glc-1-P | Glycerate | Glucosylglycerate | ||
| α-(1 → 2) | α-D-Glc-1-P | Glycerol | Glucosylglycerol | ||
| Inverting (SD) | GH65 | α,α-(1 → 1) | β-D-Glc-1-P | D-Glc/D-Glc-6-P | Trehalose/trehalose-6-P |
| α-(1 → 2) | β-D-Glc-1-P | D-Glc | Kojibiose | ||
| α-(1 → 3) | β-D-Glc-1-P | D-Glc | Nigerose | ||
| α-(1 → 4) | β-D-Glc-1-P | D-Glc | Maltose | ||
| α-(1 → 2) | β-D-Glc-1-P | Glycerol | Glucosylglycerol | ||
| α-(1 → 3) | β-D-Glc-1-P | L-Rha | α-D-Glc-(1 → 3)-L-Rha | ||
| GH94 | β-(1 → 2) | α-D-Glc-1-P | D-Glc | Sophorose | |
| β-(1 → 3) | α-D-Glc-1-P | D-Glc | Laminaribiose | ||
| β-(1 → 4) | α-D-Glc-1-P | D-Glc | Cellobiose | ||
| β-(1 → 4) | α-D-GlcNAc-1-P | D-GlcNAc | Chitobiose | ||
| β-(1 → 4) | α-D-Glc-1-P | d-Gluconic acid | Cellobionic acid | ||
| GH112 | β-(1 → 3) | α-D-Gal-1-P | D-GalNAc/D-GlcNAc | Galacto-N-biose/lacto-N-biose | |
| β-(1 → 4) | α-D-Gal-1-P | L-Rha | β-D-Gal-(1 → 4)-L-Rha | ||
| GH130 | β-(1 → 4) | α-D-Man-1-P | D-Glc | β-D-Man-(1 → 4)-D-Glc | |
| β-(1 → 4) | α-D-Man-1-P | D-GlcNAc | β-D-Man-(1 → 4)-D-GlcNAc | ||
| β-(1 → 2) | α-D-Man-1-P | D-Man | Mannobiose |
DD = double displacement, SD = single displacement, IR = internal return.