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. 2021 Jan 26;23:1136–1160. doi: 10.1016/j.omtn.2021.01.024

Figure 2.

Figure 2

Illustrations of various epigenetic posttranslational modifications

The nucleosome is comprised of approximately 147 bp of DNA comprising an octamer of two copies of each of the four core histone proteins H2A, H2B, H3, and H4. The histone tail is specifically modified by writing an enzyme that adds or erases the PTM shown.