Table 4.
Experiment IV (n=135) | Sham | SAH | SAH+vehicle | SAH+PF 1 mg/kg | SAH+PF 10 mg/kg | SAH+PF 100 mg/kg |
---|---|---|---|---|---|---|
24 h behavior text+brain water content | 6 | 6 | 6 | 6 | 6 | 6 |
72 h behavior test+brain water content | 6 | 6 | 6 | 6 | 6 | 6 |
24 h Evans blue extravasation | 6 | 6 | 6 | |||
24 h Immunofluorescence staining | 3 | 3 | 3 | |||
24 h Western blot assay | 6 | 6 | 6 | |||
24 h Zymography | 6 | 6 | 6 |
MAP4K4: Mitogen-activated protein kinase kinase kinase kinase 4; PF: PF-06260933; SAH: subarachnoid hemorrhage.