Table 2.
Multivariable-adjusted HRs (95% CI) of all-cause and cause-specific mortality according to the baseline status of prediabetes and diabetes
| ADA criteria | WHO/IEC criteria | |||||
|---|---|---|---|---|---|---|
| Normoglycemia | Prediabetes | Diabetes | Normoglycemia | Prediabetes | Diabetes | |
| No. of participants | 33,990 | 24,143 | 4,652 | 50,114 | 8,019 | 4,652 |
| Person-years | 191,140 | 132,527 | 23,210 | 280,813 | 42,854 | 23,210 |
| All-cause mortality | ||||||
| No. of deaths | 78 | 107 | 44 | 141 | 44 | 44 |
| Model 1* | 1.00 (Ref.) | 1.61 (1.19–2.19) | 3.12 (2.10–4.63) | 1.00 (Ref.) | 1.58 (1.12–2.24) | 2.62 (1.84–3.74) |
| Model 2† | 1.00 (Ref.) | 1.53 (1.12–2.09) | 2.66 (1.76–4.03) | 1.00 (Ref.) | 1.46 (1.02–2.09) | 2.25 (1.55–3.27) |
| Cancer-related death | ||||||
| No. of deaths | 26 | 57 | 14 | 56 | 26 | 14 |
| Model 1* | 1.00 (Ref.) | 2.41 (1.48–3.92) | 2.68 (1.36–5.30) | 1.00 (Ref.) | 2.10 (1.30–3.40) | 1.86 (1.02–3.41) |
| Model 2† | 1.00 (Ref.) | 2.37 (1.45–3.89) | 2.54 (1.25–5.15) | 1.00 (Ref.) | 2.03 (1.24–3.32) | 1.75 (0.93–3.28) |
| CVD-related death | ||||||
| No. of deaths | 19 | 21 | 17 | 32 | 8 | 17 |
| Model 1* | 1.00 (Ref.) | 1.23 (0.64–2.34) | 4.60 (2.26–9.36) | 1.00 (Ref.) | 1.21 (0.55–2.67) | 4.27 (2.28–7.97) |
| Model 2† | 1.00 (Ref.) | 1.00 (0.52–1.93) | 2.74 (1.29–5.81) | 1.00 (Ref.) | 0.93 (0.42–2.08) | 2.68 (1.38–5.20) |
| Other-cause death | ||||||
| No. of deaths | 33 | 29 | 13 | 52 | 10 | 13 |
| Model 1* | 1.00 (Ref.) | 1.18 (0.70–1.99) | 2.68 (1.34–5.32) | 1.00 (Ref.) | 1.15 (0.57–2.31) | 2.52 (1.33–4.77) |
| Model 2† | 1.00 (Ref.) | 1.20 (0.70–2.04) | 2.63 (1.27–5.44) | 1.00 (Ref.) | 1.16 (0.57–2.34) | 2.44 (1.24–4.79) |
Values in bold are statistically significant. Ref., reference.
*
Model 1 adjusted for age (year; continuous), sex, and worksite.
†
Model 2 additionally adjusted for BMI (kg/m2; continuous), smoking status (never smoker, former smoker, or current smoker), hypertension (yes or no), and dyslipidemia (yes or no).