Table 4.
Correlations between BMI and all cardiovascular and kidney health outcome measures in youth with T1D
| BMI | ||
|---|---|---|
| R2 | P value | |
| Vital sign | ||
| HR (bpm) | 0.30 | 0.02 |
| SBP (mmHg) | 0.36 | <0.01 |
| DBP (mmHg) | 0.34 | <0.01 |
| SBP percentile | 0.32 | <0.01 |
| DBP percentile | 0.29 | <0.01 |
| Prevalence of hypertension | 0.25 | <0.01 |
| PP (mmHg) | 0.18 | 0.04 |
| MAP (mmHg) | 0.40 | <0.01 |
| Kidney function measure | ||
| Serum creatinine (mg/dL) | 0.16 | 0.08 |
| ACR | −0.13 | 0.15 |
| Prevalence of microalbuminuria | −0.13 | 0.15 |
| eGFR (FAS) (mL/min/1.73 m2) | −0.07 | 0.42 |
| Prevalence of hyperfiltration | −0.12 | 0.17 |
| Laboratory measure | ||
| Adiponectin (µg/mL) | −0.20 | 0.02 |
| Leptin (ng/mL) | 0.61 | <0.01 |
| hs-CRP (mg/L) | 0.60 | <0.01 |
| BNP (pg/mL) | 0.13 | 0.44 |
| Peripheral vascular function measure | ||
| RHI | −0.08 | 0.61 |
| BA distensibility (mmHg−1) | −0.29 | 0.04 |
| Central vascular function measure | ||
| AA WSSMAX (dyne/cm2) | 0.13 | 0.44 |
| AA WSSTA (dyne/cm2) | −0.09 | 0.62 |
| AA PWV (m/s) | −0.04 | 0.84 |
| AA RAC (%) | −0.15 | 0.43 |
| AA OSI | 0.40 | 0.02 |
| AA distensibility (10−3 mmHg−1) | −0.27 | 0.11 |
| DA WSSMAX (dyne/cm2) | −0.23 | 0.18 |
| DA WSSTA (dyne/cm2) | 0.02 | 0.89 |
| DA PWV (m/s) | 0.33 | 0.04 |
| DA RAC (%) | −0.03 | 0.87 |
| DA OSI | 0.18 | 0.32 |
| DA distensibility (10−3 mmHg−1) | 0.21 | 0.25 |
| Cardiopulmonary fitness measure | ||
| VO2 peak (mL/min/kg) | −0.51 | <0.01 |
| VO2 peak (mL/min/lean kg) | −0.25 | 0.02 |
AA, ascending aorta; BA, brachial artery; DA, descending aorta; FAS, full age spectrum; WSSMAX, maximum WSS; WSSTA, time average WSS.