Figure 2.

Cardiovascular effectiveness and safety outcomes in subgroups of 1:1 PS-matched initiators of SGLT2i vs. GLP-1RA by history of CVD. History of CVD is defined as history of myocardial infarction, unstable angina, coronary atherosclerosis and other forms of chronic ischemic heart disease, coronary procedure, heart failure, ischemic or hemorrhagic stroke, transient ischemic attack, peripheral arterial disease or surgery, or lower-extremity amputation. Patients with CVD, 41,308; patients without CVD, 48,658. ²Hospitalization for myocardial infarction, ischemic or hemorrhagic stroke, or cardiovascular mortality. ³Hospitalization for myocardial infarction, ischemic or hemorrhagic stroke, cardiovascular mortality, or HHF. ⁴Hospitalization for myocardial infarction, ischemic or hemorrhagic stroke, all-cause mortality, or HHF. PY, person-years.