Table 1.
Participant description
| NHW | HW | NHB | Overall ANOVA P | |
|---|---|---|---|---|
| Biometric | ||||
| No. of participants | 39 | 50 | 12 | |
| Age, y | 16 (15-17) | 15 (13-16.3) | 16.5 (15-17.8) | .253 |
| BMI, kg/m2 | 35.2 (31.3-36.8) | 35.1 (31.9-38.8) | 38.5 (36.5-42.0)a | .042 |
| BMI, % | 98.3 (96.8-98.7) | 98.5 (97.2-99.1) | 99.2 (97.9-99.4) | .051 |
| BMI z score | 1.99 ± 0.06 | 2.08 ± 0.06 | 2.24 ± 0.12 | .179 |
| Waist circumference, cm | 101 ± 2 | 106 ± 2 | 113 ± 3b | .008 |
| Hip circumference, cm | 116 ± 1 | 116 ± 2 | 123 ± 3 | .134 |
| Waist/Hip ratio | 0.87 (0.83-0.92) | 0.91 (0.87-0.96) | 0.92 (0.90-0.95) | .059 |
| Systolic blood pressure, mm Hg | 122 ± 9 | 120 ± 9 | 112 ± 8b,d | .011 |
| Diastolic blood pressure, mm Hg | 73 ± 9 | 72 ± 8 | 67 ± 9 | .111 |
| Measurements of hyperandrogenism | ||||
| Total testosterone, ng/dL | 43.5 (35.8-57.0) | 35.0 (28.8-48.0) | 57 (36.5-96.3)d | .009 |
| SHBG, nmol/L | 21.5 (14.9-31.9) | 15.6 (12.1-20.3)a | 18.9 (13.3-27.7) | .018 |
| FAI | 7.2 (4.9-12.1) | 8.4 (6.1-11.0) | 10.4 (5.8-14.2) | .393 |
| Free testosterone, ng/dL | 7.6 (5.8-11.3) | 7.3 (5.2-9.9) | 9.5 (6.8-14.5) | .386 |
| Hirsutism, FGS scale | 6 (2-13) | 6 (3-10) | 8 (3-12) | .840 |
Data are mean ± SD or median (25th-75th). Significant P values are in bold.
Abbreviations: ANOVA, analysis of variance; BMI, body mass index; FAI, free androgen index; FGS, Ferriman-Gallwey score; HW, Hispanic White; NHB, non-Hispanic Black; NHW, non-Hispanic White; SHBG, sex hormone–binding globulin.
a Post hoc P less than .05 to .01 compared to HW participants.
b Post hoc P less than .01 to .001 compared to NHW participants.
c Post hoc P less than .001 compared to NHW participants.
d Post hoc P less than .05 to .01 compared to HW participants.