Table 1.
Clinicopathological characteristics of the 60 patients with CINs
| Parameters | Numbers | Percent |
|---|---|---|
| Age at diagnosis, (Mean;range) | 33.0 ± 8.8 | 18–65 |
| Smoking history | ||
| Yes | 5 | 8.3% |
| No | 55 | 91.7% |
| Drinking | ||
| Yes | 10 | 16.7% |
| No | 50 | 83.3% |
| Education | ||
| Primary | 1 | 1.7% |
| Secondary | 20 | 38.3% |
| College and above | 36 | 60.0% |
| Fertility status | ||
| Nulliparous | 26 | 43.3% |
| Pluriparous | 34 | 56.7% |
| Menopausal status | ||
| Pre-menopausal | 57 | 95% |
| Post-menopausal | 3 | 5% |
| BMI | ||
| Normal(18.5-25) | 46 | 76.7% |
| Overweight(> 25) | 6 | 10.0% |
| Underweight(< 18.5) | 8 | 13.3% |
| Monthly income | ||
| ≤10000 | 34 | 56.7% |
| >10000 | 26 | 43.3% |
| Presentation | ||
| Contact bleeding | 3 | 5% |
| Symptomless | 57 | 95% |
| Screening history | ||
| Ever | 27 | 45% |
| Never | 33 | 55% |
| Age at first intercourse (Mean;range) | 22.0 ± 2.6 | 18-31 |
| Sex partners | ||
| One | 42 | 70.0% |
| More than one | 18 | 30.0% |
| Referral Cytology | ||
| NILM | 26 | 43.3% |
| ASC-US | 12 | 20.0% |
| ASC-H | 5 | 8.3% |
| LISL | 9 | 15.0% |
| HISL | 8 | 13.3% |
| HR-HPV infection | ||
| Yes | 60 | 100% |
| No | 0 | |
| CINs detected by | ||
| Biopsy | 16 | 26.7% |
| LEEP/CKC | 44 | 73.3% |
| Pathological diagnosis | ||
| CIN1 | 27 | 45.0% |
| CIN2 | 17 | 28.3% |
| CIN3 | 16 | 26.7% |
| E6/E7mRNA | ||
| Positive | 35 | 58.3% |
| Negative | 25 | 42.7% |
| p16 | ||
| Positive | 36 | 60% |
| Negative | 24 | 40% |
| Ki67 | ||
| Positive | 42 | 70% |
| Negative | 18 | 30% |
Monthly income was the average monthly income of an individual family
NILM Negative for intraepithelial lesion or malignancy, ASCUS Atypical squamous cells of undetermined significance, ASC-H Atypical cells cannot exclude high grade, BMI Body mass index