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. 2021 Feb 19;16:13. doi: 10.1186/s13000-021-01072-9

Table 2.

Staining patterns of HPV E6/E7 mRNA in situ hybridization in CIN2 and CIN3 n(%)

CIN2+ (n = 16) CIN3+ (n = 15)
BSE 10 (62.5) 10 (66.7)
UME 5 (31.3) 3 (20.0)
LME 1 (6.2) 2 (13.3)

UME Signals staining confined in upper middle epithelial layers, LME Signals staining confined in lower middle epithelial layers, BSE Signals staining basal up to surface epithelium