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. 2021 Feb 20;16:150. doi: 10.1186/s13018-021-02284-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Non-target UHPLC-QE-MS analysis confirmed the existence of Moringa oleifera in the serum of rats that received oral dosing of Moringa leaf solution. HPLC analysis shows the differences in drug-containing serum from rats administrated Moringa leaf solution for three consecutive days (right panels) and blank serum components from rats administrated control saline (left panels). The differences in components between the two sets of samples are significant in both the negative ion mode (upper panels) and the positive ion mode (lower panels), as indicated by the different patterns of peaks. Further targeted analyses are needed to identify what ingredients the specific peaks are