Table 3.
Subanalysis of primary and secondary outcomes: open esophagectomy and minimally invasive esophagectomy
|
|
Studies
|
Participants
|
Younger
|
Older
|
RR
|
95%CI
|
P
value
|
|
| n | n | % | % | |||||
| Primary outcomes | ||||||||
| Anastomotic leak | ||||||||
| OE | 2 | 545 | 12.08 | 13.85 | 1.1307 | 0.2235 | 5.7199 | 0.5120 |
| MIE | 2 | 812 | 18.76 | 18.54 | 0.9996 | 0.1877 | 5.3243 | 0.9979 |
| 30-d mortality rate | ||||||||
| OE | 1 | 253 | 0.43 | 5.00 | 11.6500 | 0.7568 | 179.3310 | 0.0784 |
| MIE | 2 | 812 | 2.42 | 3.97 | 1.7320 | 0.0002 | 12493.0189 | 0.5761 |
| 90-d mortality rate | ||||||||
| OE | 2 | 403 | 0.60 | 2.86 | 6.8396 | 0.0279 | 1675.2496 | 0.1410 |
| MIE | 2 | 812 | 5.60 | 25.71 | 2.1859 | 0.2111 | 22.6353 | 0.1471 |
| In-hospital morality rate | ||||||||
| OE | 1 | 292 | 8.10 | 24.44 | 3.0189 | 1.5547 | 5.8620 | 0.0011 |
| MIE | 1 | 446 | 3.08 | 4.49 | 1.4586 | 0.4757 | 4.4730 | 0.5091 |
| Secondary outcomes | ||||||||
| Chylothorax | ||||||||
| OE | 1 | 292 | 3.24 | 2.22 | 0.6861 | 0.0879 | 5.3534 | 0.7193 |
| MIE | 1 | 446 | 8.12 | 7.87 | 0.9682 | 0.4385 | 2.1377 | 0.9363 |
| Pneumonia | ||||||||
| OE | 2 | 545 | 21.04 | 47.69 | 2.1531 | 0.0639 | 72.5068 | 0.2205 |
| MIE | 1 | 446 | 32.77 | 31.46 | 0.9600 | 0.6828 | 1.3497 | 0.8141 |
Standardized mean difference instead of relative risk. RR: Relative risk; 95%CI: 95% confidence interval. OE: Open esophagectomy; MIE: Minimally invasive esophagectomy.