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. 2021 Feb 16;12(1):96–102. doi: 10.1515/tnsci-2021-0011

Figure 1.

Figure 1

A hypothetical model of the possible mechanism of acupuncture for the treatment of autism. Acupuncture or electric acupuncture (EA) at specific acupoints with a certain frequency alleviates impaired social behaviors by directly up-regulating the oxytocin level in the hypothalamus or implicitly activating the endogenous cannabinoid, 5-HT, or DA signal pathway. OT: oxytocin; OTR: oxytocin receptor; AEA: anandamide; NAc: nucleus accumbens; VTA: Ventral tegmental area.