Table 2.
Symptom scores and remission time before and after treatment in the two groups
|
Group
|
PPI (n = 12)
|
WMT (n = 15)
|
P
value1
|
| Pre-GERDQ (median; IQR) | 12 (9, 13.75) | 12 (10, 12) | 0.746 |
| Post-GERDQ (median; IQR) | 11 (8.25, 13.5) | 7 (7, 8) | 0.004 |
| Intra-group, P value2 | 0.477 | 0.003 | |
| Pre-RDQ (median, IQR) | 26 (18, 33) | 23 (16, 25) | 0.203 |
| Post-RDQ (median, IQR) | 20.5 (12.75, 26) | 8 (6, 12) | 0.003 |
| Intra-group, P value | 0.005 | 0.002 | |
| Remission time (median, IQR; mo) | 2 (0, 4) | 8 (3, 17) | 0.002 |
1
The RDQ and GERDQ scores between two groups were analyzed by non-parametric Mann-Whitney test.
2
The intra-group RDQ and GERDQ scores were analyzed by non-parametric Wilcoxon signed-rank test.
WMT: Washed microbiota transplantation; PPI: Proton pump inhibitors; RDQ: Reflux disease questionnaire; GERDQ: Gastroesophageal reflux disease questionnaire; IQR: Interquartile range.