Table 1.

SPIRIT schedule of of enrolment, interventions and assessments

	Visit 1 research nurse	Visit 2 research nurse	Email or phone contacts	Visit 3 research nurse	Visit 4 research nurse
Timing	Week −1	Week 0	Weeks 1–24	Week 12	Week 24
Case record form	A	B, M, Q		C, M, X	C, H, M, Q, X
General data
Eligibility criteria	X	X
Age and sex	X
Ethnicity	X
Informed consent	X
Clinical history	X
Record or obtain ABI	X
Clinical information
Concomitant medications		X		X	X
Compression system		X		X
Ulcer measurement (max W×L)	X	X		X
Photograph ulcer		X		X	X
Ulcer healing				X	X
Other data collection
Ulcer-related pain to 12 weeks		X	X	X
Exercise adherence to 24 weeks			X		X
Quality of life measures		X			X
Ulcer-related infection				X	X
2-Minute Walk Test		X		X	X
Adverse events			X	X	X
Health resource use					X
End of trial participant survey					X
Treatment allocation
Wound solution		X
Exercise programme		X

ABI, Ankle Brachial Index; SPIRIT, Standard Protocol Items: Recommendations for Interventional Trials.