Table 2.

Flow chart of patient follow-up

	Screening	Day 0 inclusion	Study period	Death/D90
Baseline information
Demographic data and history	√	√
Inclusion and exclusion criteria	√
Written informed consent	√
Vital signs		√
APCHEII/SOFA		√	√D1, 3, 7, 14, 28
Efficacy observation
Mechanical ventilation		√	√
Treatment with vesopressor		√	√
CRRT initiation and application		√	√
UO and diuretic application		√	√
Renal function recovery			√D28	√
UCG and ECG			√D1, D14
Laboratory tests	√	√	√D1, 3, 7, 14
Biomarkers and inflammatory factors		√	√D1, 3, 7
Safety observation
Complications of CRRT		√	√
Adverse event		√	√
Additional observation
Total cost of CRRT				√
ICU and hospital LOS				√
Alive or dead status			√D28, 60	√

APCHEII, Acute Physiology and Chronic Health Evaluation II; CRRT, continuous renal replacement therapy; D90, day 90; LOS, length of stay; SOFA, Sequential Organ Failure Assessment; UCG, ultrasonic cardiogram; UO, urine output.