Table 3.
Physical and Chemical Properties and Stability Data of LVTT-PLGA MS. Data Represents the Mean ± SD (n = 3)
| Formulation | Temperature | Time | Particle Size (µm) | Encapsulation Efficiency (%) | Drug Loading (%) | Polydispersity Index | Zeta Potentials (mV) |
|---|---|---|---|---|---|---|---|
| LVTT-PLGA MS | Room temperature | 0 day | 12.3±2.1 | 87.3±5.6 | 27.6±2.9 | 0.21 | −19.4±1.5 |
| 40 ± 2°C | 30 days | 13.7±3.2 | 85.2±7.2 | 26.2±2.5 | 0.23 | −20.2±1.3 | |
| 60 days | 14.5±3.3 | 83.1±6.7 | 25.1±2.3 | 0.22 | −21.3±1.6 | ||
| 5 ± 2°C | 30 days | 12.6±2.3 | 86.6±4.9 | 26.7±2.3 | 0.24 | −22.1±1.4 | |
| 60 days | 12.8±2.1 | 85.5±6.1 | 26.2±2.2 | 0.25 | −22.5±1.7 |
Note: After statistics, there is no significant difference between the data of each group and the parameters of initial state (0 day).