. Author manuscript; available in PMC: 2021 Feb 20.

Published in final edited form as: J Cardiovasc Electrophysiol. 2019 Sep 25;30(11):2508–2515. doi: 10.1111/jce.14176

TABLE 2.

Prevalence and odds ratios of physical, cognitive, and psychosocial impairments in relation to high anticoagulation burden among elderly adults with atrial fibrillation receiving an anticoagulant

Impairment and its prevalence		Odds ratio (95% confidence interval)
Impairment and its prevalence		Unadjusted	Model 1	Model 2	Model 3
Frailty	145 (14%)	2.0 (1.3-3.1)	0.9 (0.5-1.5)	1.3 (0.7-2.4)	1.4 (0.7-2.5)
Cognitive impairment	435 (42%)	1.0 (0.7-1.3)	0.8 (0.6-1.1)	0.8 (0.5-1.2)	0.8 (0.5-1.2)
Social isolation	133 (13%)	1.5 (1.0-2.2)	1.6 (1.1-2.5)	1.5 (0.9-2.4)	1.5 (1.0-2.4)
Visual impairment	361 (35%)	2.1 (1.5-2.7)	1.6 (1.1-2.1)	1.6 (1.1-2.3)	1.7 (1.2-2.4)
Hearing impairment	376 (36%)	1.2 (0.9-1.6)	1.1 (0.8-1.5)	1.1 (0.8-1.6)	1.1 (0.8-1.6)
Depression	296 (29%)	3.7 (2.8-5.0)	2.5 (1.7-3.7)	2.4 (1.5-3.6)	2.4 (1.6-3.7)
Anxiety	245 (24%)	3.5 (2.6-4.8)	2.1 (1.5-3.1)	1.8 (1.2-2.7)	1.8 (1.2-2.7)

Note: Model 1: all geriatric and mood impairments and symptoms of atrial fibrillation; Model 2: variables controlled for in model 1 and age, sex, education, income, insurance, and provider type; Model 3: variables controlled for in model 2 and CHADSVASC and HAS-BLED.