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. 2021 Feb 16;14:719–728. doi: 10.2147/DMSO.S288482

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© 2021 Ji et al.

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miR-7a regulated the PI3K/Akt cascade by targeting IRS-2. The Endothelial cells and Retinal pericytes received transfection of miR-7a mimic, mimic control, miR-7a inhibitor or inhibitor control. (A and B) Protein levels of IRS-2 and proteins of PI3K/Akt cascade. (C and D) Western blot analysis for expression of PI3K/Akt proteins in Endothelial cells and Retinal pericytes. The results are presented as mean ± standard deviation (n=3). *P<0.05 compared to mimic control, ^@P<0.05 compared to inhibitor control.