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. 2021 Feb 13;2021:8828331. doi: 10.1155/2021/8828331

Table 4.

Effects of solvent fractions on castor oil-induced enteropooling in mice.

Dose administered Mean volume of small intestinal content (gm) % inhibition Mean weight of small intestinal content (ml) % inhibition
Control 0.76 ± 0.04 0.81 ± 0.01
CF 100 mg/kg 0.69 ± 0.02b∗∗∗ 9.20 0.69 ± 0.018ab∗∗∗ 14.80
CF 200 mg/kg 0.58 ± 0.02a∗∗b∗∗∗ 23.60 0.6 ± 0.02a∗∗b∗∗∗ 26.00
CF 400 mg/kg 0.40 ± 0.04a∗∗∗ 47.30 0.48 ± 0.02a∗∗∗ 40.70
EA 100 mg/kg 0.62 ± 0.21ab∗∗∗ 18.40 0.6 ± 0.02a∗∗b∗∗∗ 26.00
EA 200 mg/kg 0.53 ± 0.09a∗∗b 30.20 0.51 ± 0.02a∗∗∗b 37.00
EA 400 mg/kg 0.36 ± 0.14a∗∗∗ 52.60 0.38 ± 0.01a∗∗∗ 53.00
AF 100 mg/kg 0.68 ± 0.018b∗∗∗ 10.50 0.71 ± 0.01ab∗∗∗ 12.30
AF 200 mg/kg 0.55 ± 0.02a∗∗b∗∗∗ 27.60 0.59 ± 0.01a∗∗b∗∗∗ 27.10
AF 400 mg/kg 0.45 ± 0.08a∗∗∗ 40.70 0.43 ± 0.02a∗∗∗ 47.00
Loperamide 3 mg/kg 0.36 ± 0.02a∗∗∗ 52.60 0.4 ± 0.01a∗∗∗ 50.60

Data are expressed as mean ± SEM (n = 6); analysis was performed with One-Way ANOVA followed by Tukey test; acompared to negative control; bcompared to loperamide 3 mg/kg; P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001; CF, chloroform fraction; EAF: ethyl acetate fraction; AF: aqueous fraction; negative controls received 10 ml/kg distilled water.