Table 2.

CEST fitting parameters for the sample RNA data

	AIC	RMS	kex	pb	δA0	δB0	R1A	R1B	R2A	R2B
TROTT–PALMER-SD	− 533	0.014	163.2 ± 24.2	0.08 ± 0.006	2.8 ± 0.02	− 1.3 ± 0.01	2.4 ± 0.01	2.4 ± 0.01	19.4 ± 1.9	148.1 ± 17.5
TROTT–PALMER	− 531	0.014	157.5 ± 20.9	0.08 ± 0.005	2.8 ± 0.02	− 1.3 ± 0.01	2.4 ± 0.01	2.4 ± 0.01	19.2 ± 1.7	155.1 ± 19.2
BALDWIN–KAY	− 528	0.014	164.9 ± 21.4	0.08 ± 0.004	2.8 ± 0.02	− 1.3 ± 0.01	2.4 ± 0.01	2.4 ± 0.01	21.3 ± 1.9	153.0 ± 17.0
LAGUERRE	− 432	0.020	300.9 ± 30.2	0.07 ± 0.005	2.9 ± 0.03	− 1.4 ± 0.03	2.5 ± 0.01	2.5 ± 0.01	11.9 ± 2.2	11.9 ± 2.2
EXACT1	− 648	0.010	109.9 ± 13.6	0.10 ± 0.005	2.8 ± 0.01	− 1.3 ± 0.01	2.0 ± 0.03	2.0 ± 0.03	25.6 ± 1.1	153.4 ± 11.0
EXACT0	− 647	0.010	107.5 ± 13.7	0.10 ± 0.006	2.8 ± 0.01	− 1.3 ± 0.01	2.0 ± 0.03	2.2 ± 0.09	25.7 ± 1.2	154.0 ± 9.2
EXACT2	− 518	0.015	243.7 ± 23.5	0.07 ± 0.006	2.8 ± 0.01	− 1.4 ± 0.02	2.2 ± 0.04	2.5 ± 0.37	16.3 ± 1.0	16.3 ± 1.0
EIGENEXACT1	− 519	0.015	161.8 ± 25.2	0.08 ± 0.006	2.8 ± 0.02	− 1.3 ± 0.01	2.4 ± 0.01	2.4 ± 0.01	20.7 ± 2.2	145.6 ± 21.7
Literature			109.0 ± 8.0	0.10 ± 0.003	− 4.09 ± 0.01		2.4 ± 0.01	2.4 ± 0.01	24.1 ± 0.8	147.0 ± 7.0

The best fit to the data is shown in bold. Literature values are for the RNA C₈ atom at 30 ºC from (Zhao et al. 2014)