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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Reprod Toxicol. 2020 Nov 30;99:56–64. doi: 10.1016/j.reprotox.2020.11.014

Table 2.

Distribution of urinary phthalate metabolite concentrations (ng/mL) among women (n=56) and mean (n=43) undergoing IVF

Phthalate Metabolite Geometric Mean Geometric SD Minimum 25th Percentile 50th Percentile 75th Percentile Maximum ≥LOD (%)
MEP
 Women 30.0 3.66 1.44 10.8 29.5 72.6 971 100
 Men 18.9 2.87 <LOD 8.96 15.7 42.2 601 98.0
MBP
 Women 16.1 2.82 <LOD 7.55 14.1 26.9 324 98.0
 Men 9.72 2.59 1.75 4.97 7.59 17.0 252 100
ΣLMWa
 Women 258 3.19 18.4 120 240 511 5242 -
 Men 155 2.82 13.5 83.2 125 330 3118 -
MPP
 Women <LOD 1.05 <LOD <LOD <LOD <LOD 0.36 5.0
 Men <LOD 1.14 <LOD <LOD <LOD <LOD 1.15 9.0
MHxP
 Women 3.46 1.56 0.78 2.38 3.53 4.96 10.7 100
 Men 2.05 1.64 0.35 1.26 1.76 3.46 10.0 100
MEHP
 Women 3.08 3.58 <LOD 0.66 2.03 3.50 114 98.0
 Men 1.86 2.60 0.13 0.50 1.42 2.68 325 100
MEHHP
 Women 2.24 2.53 0.79 3.88 6.87 14.4 105 100
 Men 6.17 2.78 0.69 2.56 4.30 9.64 315 100
MECPP *
 Women 19.5 2.94 2.39 8.35 16.4 46.5 373 100
 Men R.7 3.33 1.24 5.05 11.2 20.5 448 100
ΣDEHPb *
 Women 108 3.06 16.3 44.3 86.6 223 1895 98.0
 Men 69.0 3.28 6.87 31.2 56.7 108 3673 100
MiNP
 Women <LOD 1.69 <LOD <LOD <LOD <LOD 10.5 9.0
 Men <LOD 1.68 <LOD <LOD <LOD <LOD 5.13 14.0
MiDP
 Women <LOD <LOD <LOD <LOD <LOD <LOD 9.64 4.0
 Men <LOD <LOD <LOD <LOD <LOD <LOD <LOD 0.0
MCHP
 Women <LOD 1.06 <LOD <LOD <LOD <LOD 0.54 2.0
 Men <LOD <LOD <LOD <LOD <LOD <LOD <LOD 0.0
MBzP *
 Women 3.10 4.10 <LOD 0.99 2.31 5.61 52.3 98.0
 Men 1.85 2.85 0.29 0.66 1.40 2.94 38.4 100
ΣHMWc *
 Women 148 2.72 24.3 67.3 131 365 1936 -
 Men 89.5 3.01 13.2 40.5 74.7 143 3848 -
a

ΣLMW (nmol/mL) as the molar sum of MEP, MBP, and MPP;

b

ΣDEHP (nmol/mL) as the molar sum of MEHP, MEHHP, and MECPP;

c

ΣHMW (nmol/mL) as the molar sum of MHxP, MEHP, MEHHP, MECPP, MiNP, and MBzP;

*

p<0.05 for the difference between women and men using Wilcoxon signed rank test.

Abbreviations: IVF, in vitro fertilization; LOD, limit of detection; MBP, monobutyl phthalate; MBzP, monobenzyl phthalate; MCHP, monocyclohexyl phthalate; MECPP, mono(2-ethyl-5-carboxypentyl) phthalate; MEHHP, mono (2-ethyl-5-hydroxyhexyl) phthalate; MEHP, mono-(2-ethylhexyl) phthalate; MEP, monoethyl phthalate; MHxP, monohexyl phthalate; MiDP, mono-isodecyl phthalate; MiNP, mono-isononyl phthalate; MPP, mono-n-pentyl phthalate