Table 2.
Phthalate Metabolite | Geometric Mean | Geometric SD | Minimum | 25th Percentile | 50th Percentile | 75th Percentile | Maximum | ≥LOD (%) |
---|---|---|---|---|---|---|---|---|
MEP | ||||||||
Women | 30.0 | 3.66 | 1.44 | 10.8 | 29.5 | 72.6 | 971 | 100 |
Men | 18.9 | 2.87 | <LOD | 8.96 | 15.7 | 42.2 | 601 | 98.0 |
MBP | ||||||||
Women | 16.1 | 2.82 | <LOD | 7.55 | 14.1 | 26.9 | 324 | 98.0 |
Men | 9.72 | 2.59 | 1.75 | 4.97 | 7.59 | 17.0 | 252 | 100 |
ΣLMWa | ||||||||
Women | 258 | 3.19 | 18.4 | 120 | 240 | 511 | 5242 | - |
Men | 155 | 2.82 | 13.5 | 83.2 | 125 | 330 | 3118 | - |
MPP | ||||||||
Women | <LOD | 1.05 | <LOD | <LOD | <LOD | <LOD | 0.36 | 5.0 |
Men | <LOD | 1.14 | <LOD | <LOD | <LOD | <LOD | 1.15 | 9.0 |
MHxP | ||||||||
Women | 3.46 | 1.56 | 0.78 | 2.38 | 3.53 | 4.96 | 10.7 | 100 |
Men | 2.05 | 1.64 | 0.35 | 1.26 | 1.76 | 3.46 | 10.0 | 100 |
MEHP | ||||||||
Women | 3.08 | 3.58 | <LOD | 0.66 | 2.03 | 3.50 | 114 | 98.0 |
Men | 1.86 | 2.60 | 0.13 | 0.50 | 1.42 | 2.68 | 325 | 100 |
MEHHP | ||||||||
Women | 2.24 | 2.53 | 0.79 | 3.88 | 6.87 | 14.4 | 105 | 100 |
Men | 6.17 | 2.78 | 0.69 | 2.56 | 4.30 | 9.64 | 315 | 100 |
MECPP * | ||||||||
Women | 19.5 | 2.94 | 2.39 | 8.35 | 16.4 | 46.5 | 373 | 100 |
Men | R.7 | 3.33 | 1.24 | 5.05 | 11.2 | 20.5 | 448 | 100 |
ΣDEHPb * | ||||||||
Women | 108 | 3.06 | 16.3 | 44.3 | 86.6 | 223 | 1895 | 98.0 |
Men | 69.0 | 3.28 | 6.87 | 31.2 | 56.7 | 108 | 3673 | 100 |
MiNP | ||||||||
Women | <LOD | 1.69 | <LOD | <LOD | <LOD | <LOD | 10.5 | 9.0 |
Men | <LOD | 1.68 | <LOD | <LOD | <LOD | <LOD | 5.13 | 14.0 |
MiDP | ||||||||
Women | <LOD | <LOD | <LOD | <LOD | <LOD | <LOD | 9.64 | 4.0 |
Men | <LOD | <LOD | <LOD | <LOD | <LOD | <LOD | <LOD | 0.0 |
MCHP | ||||||||
Women | <LOD | 1.06 | <LOD | <LOD | <LOD | <LOD | 0.54 | 2.0 |
Men | <LOD | <LOD | <LOD | <LOD | <LOD | <LOD | <LOD | 0.0 |
MBzP * | ||||||||
Women | 3.10 | 4.10 | <LOD | 0.99 | 2.31 | 5.61 | 52.3 | 98.0 |
Men | 1.85 | 2.85 | 0.29 | 0.66 | 1.40 | 2.94 | 38.4 | 100 |
ΣHMWc * | ||||||||
Women | 148 | 2.72 | 24.3 | 67.3 | 131 | 365 | 1936 | - |
Men | 89.5 | 3.01 | 13.2 | 40.5 | 74.7 | 143 | 3848 | - |
ΣLMW (nmol/mL) as the molar sum of MEP, MBP, and MPP;
ΣDEHP (nmol/mL) as the molar sum of MEHP, MEHHP, and MECPP;
ΣHMW (nmol/mL) as the molar sum of MHxP, MEHP, MEHHP, MECPP, MiNP, and MBzP;
p<0.05 for the difference between women and men using Wilcoxon signed rank test.
Abbreviations: IVF, in vitro fertilization; LOD, limit of detection; MBP, monobutyl phthalate; MBzP, monobenzyl phthalate; MCHP, monocyclohexyl phthalate; MECPP, mono(2-ethyl-5-carboxypentyl) phthalate; MEHHP, mono (2-ethyl-5-hydroxyhexyl) phthalate; MEHP, mono-(2-ethylhexyl) phthalate; MEP, monoethyl phthalate; MHxP, monohexyl phthalate; MiDP, mono-isodecyl phthalate; MiNP, mono-isononyl phthalate; MPP, mono-n-pentyl phthalate