Table 1.
Viscosity at 100 mg/ml as a function of excipient and statistics from SILCS analysis
| Actual Conc. (mg/mL) | True Viscosity (cP) | SILCS #PPI blocking poses | SILCS #Exclusive Binding Sites | |
|---|---|---|---|---|
| Control | 101.0 | 5.8 | - | |
| Arginine | 105.6 | 8.6 | 10 | 2 |
| Lysine | 102.2 | 4.6 | 14 | 2 |
| Proline | 105.0 | 5.8 | 7 | 1 |