Table 2.

GnRHa Cohort Mental Health, Well-Being, and Gender-specific Experiences Based on Designated Sex at Birth

GnRHa Cohort (N=95)
	Total Sample	Designated Female at Birth	Designated Male at Birth	t or χ² (df)	p-value
Beck Depression Inventory-Y (n=91) n (%)
Minimal Depression	65 (71.4)	32 (74.4)	33 (68.8)	1.14 (3)	0.767
Mild Depression	9 (9.9)	4 (9.3)	5 (10.4)
Moderate Depression	10 (11.0)	5 (11.6)	5 (10.4)
Severe Depression	7 (7.7)	2 (4.7)	5 (10.4)
Revised Children’s Manifest Anxiety Scale 2 (n=84) M (SD)
Total Anxiety T-score	48.37 (12.75)	45.67 (11.65)	51.2 (13.38)	2.02 (82)	0.047^*
Physiological Anxiety T-score	47.27 (11.42)	45.49 (10.6)	49.15 (12.07)	1.48 (82)	0.143
Worry T-Score	50.08 (12.80)	47.11 (11.57)	53.2 (13.42)	2.23 (82)	0.029^*
Social Anxiety T-score	47.65 (11.88)	45.53 (10.57)	49.88 (12.87)	1.69 (82)	0.094
NIH Toolbox Life Satisfaction T-Score -Parent Report (n=94) M (SD)	45.91 (11.23)	45.97 (9.61)	45.85 (12.64)	−0.05 (88.983)	0.959
Lifetime SI (n=89)^{^}
No	68 (76.4)	35 (39.3)	33 (37.1)	2.12 (1)	0.146
Yes	21 (23.6)	7 (7.9)	14 (15.7)	2.12 (1)	0.146
Lifetime SI with plan (n=21)^{^}
No	13 (14.6)	4 (4.5)	9 (10.1)	0.10 (1)	1.000
Yes	8 (8.9)	3 (3.4)	5 (5.6)	0.10 (1)	1.000
Lifetime Suicide Attempt (n=18)^{^}
No	11 (12.4)	3 (3.4)	8 (44.4)	0.42 (1)	1.000
Yes	7 (7.9)	1 (1.1)	6 (33.3)	0.42 (1)	1.000
Past 6 months SI (n=20)^{^}
No	8 (8.9)	3 (3.4)	5 (5.6)	0.36 (1)	0.642
Yes	12 (13.5)	3 (3.4)	9 (10.1)	0.36 (1)	0.642
Past 6 months SI with plan (n=8)^{^}
No	4 (4.5)	2 (2.2)	2 (2.2)	0.53 (1)	1.000
Yes	4 (4.5)	1 (1.1)	3 (3.4)	0.53 (1)	1.000
Past 6 months Suicide Attempt (n=8)^{^}
No	6 (6.7)	2 (2.2)	4 (4.5)	0.89 (1)	1.000
Yes	2 (2.2)	-	2 (2.2)	0.89 (1)	1.000
Body Esteem Scale (n=91) M (SD)
Total Scale Score	45.78 (10.80)	45.53 (11.74)	46.01 (9.97)	0.30 (89)	0.834

Note. GnRHa = gonadotropin releasing hormone agonists. M = mean; SD = standard deviation

p < 0.05

^{^}

percentages do not add up to 100% due to N/A responses due to preprogrammed skip patterns.