Table 2.

Predictive performance of miRNA-based expression signature for tumor mutational burden in CRC

Cohort	SE	SP	PPV	NPV	Accuracy	AUC
Total	0.8434	0.9866	0.9333	0.966	0.9606	0.9839
Training	0.8776	0.9956	0.9773	0.974	0.9745	0.9913
Validation	0.7941	0.973	0.871	0.9536	0.9396	0.9704

SE sensitivity, SP specificity, PPV positive predictive value, NPV negative predictive value, AUC area under the receiver operating characteristic curve