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. 2021 Jan 15;49(3):1497–1516. doi: 10.1093/nar/gkaa1269

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Relationships between fixed nucleotide substitution (FNS) frequency and non-B DNA. (A) G-quadruplexes coverage weighted by stability, (B) A-phased repeats coverage, (C) inverted repeats coverage, (D) direct repeats coverage, (E) Z-DNA motifs coverage, and (F) mirror repeats coverage. Red curves represent loess (locally estimated scatterplot smoothing) fits superimposed to the scatterplots to visualize trends. See Supplementary Figure S11 for an analogous analysis performed using SNP data.