Table 3.
Association of severe COVID-19 with number of non-cardiovascular drug classes dispensed, by care home residence
| Number of drug classes | Controls (36,738) | Cases (4251) | Rate ratio (95% CI) | p value |
|---|---|---|---|---|
| Not resident in care home (33,803 controls, 2357 cases) | ||||
| 0 | 4962 (15%) | 167 (7%) | ||
| 1 to 3 | 11,036 (33%) | 442 (19%) | 1.56 (1.29, 1.88) | 4×10−6 |
| 4 to 6 | 8492 (25%) | 578 (25%) | 2.97 (2.47, 3.59) | 4×10−30 |
| 7 to 9 | 5083 (15%) | 469 (20%) | 4.45 (3.66, 5.42) | 3×10−50 |
| 10 to 12 | 2511 (7%) | 328 (14%) | 6.6 (5.4, 8.2) | 2×10−69 |
| >12 | 1719 (5%) | 373 (16%) | 10.8 (8.8, 13.3) | 5×10−110 |
| Care home residents (2935 controls, 1894 cases) | ||||
| 0 | 40 (1%) | 32 (2%) | ||
| 1 to 3 | 261 (9%) | 167 (9%) | 2.01 (0.87, 4.63) | 0.1 |
| 4 to 6 | 800 (27%) | 395 (21%) | 1.38 (0.62, 3.09) | 0.4 |
| 7 to 9 | 821 (28%) | 574 (30%) | 1.86 (0.83, 4.17) | 0.1 |
| 10 to 12 | 585 (20%) | 425 (22%) | 2.02 (0.90, 4.55) | 0.09 |
| >12 | 428 (15%) | 301 (16%) | 1.91 (0.85, 4.30) | 0.1 |