Table 1.
Expression Profile of X13 hiPSC-Derived Erythroblasts from Spinner Culture Differentiation
| Expression Profile | Marker | Spinner 1 | Spinner 2 | Spinner 3 | Mean ± SD |
|---|---|---|---|---|---|
| Erythroid | CD235a | 63.5 | 73.5 | 68.1 | 68.4 ± 5.0 |
| Early erythroid | CD235a+ CD71+ | 44.3 | 58.5 | 51.4 | 51.4 ± 7.1 |
| Late erythroid | CD235a+ CD71− | 19.2 | 15 | 16.7 | 16.9 ± 2.1 |
| Thrombospondin receptor | CD36 | 16.8 | 29.4 | 17.5 | 21.2 ± 7.1 |
| Hematopoietic progenitor | CD45 | 13.1 | 7.6 | 10.5 | 10.4 ± 2.8 |
| Hematopoietic progenitor | CD43 | 40.7 | 34.3 | 37.8 | 37.6 ± 3.3 |
| Hematopoietic stem cell | CXCR4 | 3.74 | 3.21 | 1.84 | 2.9 ± 1.0 |
| Hematopoietic stem cell | CD133 | 0.17 | 0.09 | 0.08 | 0.12 ± 0.05 |
| Myelomonocytic cell | CD15 | 0.47 | 0.58 | 0.51 | 0.5 ± 0.05 |
| Myelomonocytic cell | CD14 | 0.17 | 0.12 | 0.12 | 0.14 ± 0.03 |
| Fetal hemoglobin | HbF | 59.6 | 85.4 | 66.3 | 70.4 ± 13.3 |
| Adult hemoglobin | HbA | 16.3 | 15.2 | 15.3 | 15.6 ± 0.69 |