Table 4.
Study protocols registered in the clinicaltrials.gov database on 22 April 2020 with sarcopenia listed as a target condition
| NCT number | Status | Conditions | Interventions | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04021706 | Recruiting | Sarcopenia | Anamorelin hydrochloride | 05-12-19 | 01-11-21 |
| Osteopenia | |||||
| NCT03995251 | Recruiting | Liver cirrhosis | Testosterone | 04-07-19 | 30-06-20 |
| NCT03867357 | Recruiting | Metastatic prostate cancer | GnRH agonist | 07-12-18 | 31-08-21 |
| Androgen deprivation therapy | |||||
| NCT03788252 | Active, not recruiting | Chronic kidney diseases | Renamezin | 23-11-18 | 01-12-20 |
| NCT03633279 | Recruiting | Liver cirrhoses | Branched chain amino acid | 22-06-18 | 01-07-20 |
| NCT03452488 | Recruiting | Sarcopenia | BIO101 | 24-05-18 | 01-12-20 |
| Gait disorders in old age | |||||
| Muscle weakness | |||||
| NCT03248271 | Withdrawn | Diabetes | Insulin Lispro | 01-10-17 | 01-10-19 |
| Sarcopenia | |||||
| Hypotension, orthostatic | |||||
| NCT03119610 | Active, not recruiting | Obesity | Oxytocin | 22-09-17 | 01-12-19 |
| Sarcopenic obesity | |||||
| Sarcopenia | |||||
| Aging | |||||
| Sedentary Lifestyle | |||||
| NCT02938923 | Recruiting | Hip fracture | Testosterone | 15-09-17 | 31-05-22 |
| Frailty | |||||
| Sarcopenia | |||||
| NCT03054168 | Active, not recruiting | Sarcopenia | Sustanon | 15-12-16 | 15-02-19 |
| Muscle hypotrophy | |||||
| Muscle atrophy | |||||
| NCT01417364 | Withdrawn | Sarcopenia | Testosterone enanthate | 01-01-16 | 01-12-17 |
| NCT02575235 | Unknown status | Sarcopenia | CPC | 01-10-15 | 01-08-16 |
| NCT02594579 | Unknown status | Vitamin D deficiency | Vitamin D3 | 01-10-15 | 01-12-16 |
| Sarcopenia | |||||
| Critical illness | |||||
| NCT02468674 | Completed | Sarcopenia | Bimagrumab | 22-07-15 | 03-12-18 |
| NCT01550107 | Completed | Sarcopenia | Allopurinol | 01-02-15 | 20-09-17 |
| NCT02333331 | Completed | Sarcopenia | Bimagrumab | 09-12-14 | 28-06-18 |
| NCT02297997 | Unknown status | Sarcopenia | Cetylpyridinium chloride | 01-11-14 | 01-11-15 |
| NCT02370745 | Completed | Sarcopenia | GLP-1 | 01-11-14 | 01-03-18 |
| Insulin actrapid | |||||
| GIP | |||||
| NCT02606279 | Terminated | HIV | Valsartan | 01-07-14 | 04-08-16 |
| Aging | |||||
| Sarcopenia | |||||
| Angiotensin receptor antagonists | |||||
| NCT04354896 | Completed | Subclinical hypothyroidism | Levothyroxine | 01-05-14 | 04-05-18 |
| Sarcopenia | |||||
| NCT01804049 | Completed | Prediabetes | Metformin | 08-04-14 | 31-08-18 |
| NCT03784495 | Completed | Sarcopenia | Melatonin | 01-01-14 | 01-06-15 |
| NCT01963598 | Completed | Sarcopenia | REGN1033 | 01-11-13 | 01-02-15 |
| NCT01898611 | Completed | Frailty syndrome | Ghrelin | 01-07-13 | 31-08-16 |
| NCT01989793 | Completed | Sarcopenia | Losartan | 01-07-13 | 01-10-16 |
| NCT01886196 | Completed | Sarcopenia | Ibuprofen | 01-04-13 | 01-07-14 |
| Osteoporosis | |||||
| NCT02327091 | Completed | Muscle weakness | Alfacalcidol | 01-04-12 | 01-12-12 |
| NCT01666522 | Completed | Sarcopenia | Vitamin D | 01-04-11 | 01-09-11 |
| NCT02305069 | Completed | Obesity | Pioglitazone | 01-10-09 | 01-09-12 |
| Sarcopenia | Insulin | ||||
| Octreotide | |||||
| NCT00891696 | Completed | Sarcopenia | Rapamycin | 01-04-09 | 01-03-15 |
| Sodium nitroprusside | |||||
| NCT00957801 | Completed | Sarcopenia | Testosterone | 01-03-09 | 01-12-15 |
| Medrol | |||||
| NCT00529659 | Completed | Sarcopenia | MK-0773 | 01-10-07 | 01-10-09 |
| NCT00509405 | Completed | Healthy | Potassium citrate | 01-07-07 | 01-05-10 |
| NCT00475501 | Completed | Male hypogonadism | Testosterone enanthate | 01-01-07 | 01-10-14 |
| Muscle atrophy | Finasteride | ||||
| Sarcopenia | |||||
| Benign prostate hypertrophy | |||||
| NCT00315146 | Completed | Obesity | Pioglitazone | 01-04-06 | 01-04-07 |
| Overweight with indications for weight loss | |||||
| NCT00690534 | Completed | Sarcopenia | Insulin regular | 01-09-05 | 01-08-12 |
| L-NMMA | |||||
| Sodium nitroprusside | |||||
| NCT00128115 | Terminated | Hip Fracture | MK0677 | 01-09-05 | 01-08-07 |
| NCT00240981 | Terminated | Sarcopenia | Testosterone | 01-01-05 | 01-12-09 |
| Hypogonadism | |||||
| Muscular diseases | |||||
| NCT00190060 | Completed | Frailty | Testosterone | 01-10-04 | 31-12-08 |
| Sarcopenia | |||||
| NCT00104572 | Completed | Hypogonadism | Androgel (Testosterone Gel) | 01-03-04 | 01-01-15 |
| Diabetes | Anastrozole (aromatase inhibitor) | ||||
| Sarcopenia | |||||
| Sarcopenia | |||||
| Depression | |||||
| NCT00183040 | Completed | Sarcopenia | Testosterone | 01-09-02 | 01-02-07 |
| Muscle weakness | Recombinant human growth hormone | ||||
| Frailty | |||||
| NCT00205686 | Completed | Healthy volunteers | DHEA | 01-04-01 | 01-09-05 |
| NCT00474279 | Completed | Aging | MK-677 | 01-07-98 | 01-06-04 |
| NCT00254371 | Completed | Aging | Androgen replacement therapy | 01-07-98 | 01-02-07 |
| Low DHEA for women | |||||
| Low testosterone and DHEA for men |
Manual selection of interventional trials studying pharmacological products