Table 2.
The factors significantly affected progression free survival and overall survival in patients treated with immunotherapy in multiparameter analysis using Cox proportional hazards regression method.
| Factor | p | Hazard ratio | 95% CI |
|---|---|---|---|
| PFS | |||
| PD-L1 expression on ≥1% of tumor cells | 0.0323 | 0.3857 | 0,1612–0.9226 |
| CG or GG genotype in rs822336 of PD-L1 gene | 0.0917 | 0.3358 | 0,0945–1.1937 |
| High miRNA-200b expression | 0.0771 | 0.528 | 0,0190–1.2266 |
| Overall model fit: χ2 = 4.88, p=0.0272 | |||
| OS | |||
| PD-L1 expression on ≥1% of tumor cells | 0.0220 | 0.3770 | 0.1636–0.8688 |
| Overall model fit: χ 2 = 13.467, p=0.0037 | |||