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. 2021 Feb 8;10:622251. doi: 10.3389/fonc.2020.622251

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Copyright © 2021 Wang, Qiu, Chen, Zhang, Yang and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of the immune infiltration subtypes in LUAD in the TCGA cohort. (A) According to 29 immune-related gene sets, three immune infiltration subtypes were identified in LUAD samples by ssGSEA. The results of the ESTIMATE algorithm are also shown in the heatmap. (B) The immune score calculated by the ESTIMATE algorithm in different immune infiltration subtypes. (C) Relative fractions of 14 immune cells in different immune infiltration subtypes. The red box indicated that the relative expression of immune cells increased or decreased in the three immune infiltration subtypes. (D) Kaplan-Meyer survival curve of the three immune infiltration subtypes in the TCGA cohort. *P < 0.05; **P < 0.01; ***P < 0.001.