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. 2020 May 11;27(3):380–390. doi: 10.1177/1352458520918978

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© The Author(s), 2020

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Axonal loss, cortical pathology, and WM pathology in multiple sclerosis. The first two rows show bar plots displaying group differences between controls, MS cortical normal-appearing gray matter (cNAGM), and MS lesioned cortex (MS lesion) on (a) axonal density, (b) neuronal density, (c) neuronal volume, (d) myelin density, and (e) microglia density. The bottom row shows bar plots displaying group differences between control normal-appearing white matter (NAWM), MS NAWM, and MS white matter lesions (WML) on (f) axial diffusivity (AD), (g) radial diffusivity (RD), (h) mean diffusivity (MD), and (i) Fractional anisotropy (FA). Dots represent data points of tissue blocks of subjects.

*p < 0.05; **p ⩽ 0.01; ***p ⩽ 0.001.