Table 1.
Demographic and clinical data of subjects.
| Case | Sex | Age of death (y) | Age of diagnosis (y) | Disease duration (y) | MS type | Post-mortem delay to autopsy (h:m) | Cause of death | Number of available tissue blocks |
|---|---|---|---|---|---|---|---|---|
| MS | ||||||||
| 1 | M | 66 | 41 | 25 | PPMS | 8:55 | Euthanasia | 5 |
| 2 | M | 62 | 21 | 41 | SPMS | 9:20 | Euthanasia | 3 |
| 3 | F | 52 | 21 | 31 | PPMS | 7:40 | Euthanasia | 1 |
| 4 | M | 51 | 30 | 21 | SPMS | 9:40 | Euthanasia | 4 |
| 5 | M | 83 | 38 | 45 | SPMS | 7:00 | Pneumonia | 5 |
| 6 | F | 63 | 30 | 33 | SPMS | 7:20 | Euthanasia | 1 |
| 7 | F | 40 | 32 | 8 | SPMS | 7:10 | Ileus | 1 |
| 8 | F | 71 | 39 | 32 | SPMS | 7:55 | Euthanasia | 5 |
| 9 | F | 57 | 28 | 29 | SPMS | 8:55 | Euthanasia | 5 |
| 10 | F | 49 | 49 | 25 | SPMS | 7:45 | Pneumonia | 3 |
| 11 | F | 83 | 23 | 60 | SPMS | 7:40 | Euthanasia | 4 |
| 12 | F | 62 | 39 | 23 | SPMS | 8:45 | Euthanasia | 4 |
| 13 | F | 65 | 25 | 40 | SPMS | 9:40 | Sepsis | 3 |
| 14 | F | 77 | 51 | 26 | PPMS | 8:35 | Colorectal cancer | 5 |
| 15 | F | 81 | 30 | 51 | SPMS | 6:10 | Respiratory insufficiency | 2 |
| 16 | M | 76 | 34 | 42 | PPMS | 8:30 | Euthanasia | 3 |
| Controls | ||||||||
| 1 | M | 77 | 11:35 | Pneumonia | 6 | |||
| 2 | F | 69 | 13:00 | Pulmonary embolism | 6 | |||
| 3 | M | 59 | 8:00 | Euthanasia | 6 | |||
| 4 | F | 71 | 6:50 | Lung cancer | 6 | |||
| 5 | M | 74 | 16:00 | Colorectal cancer | 6 | |||
| 6 | M | 72 | 11:45 | Esophageal cancer | 6 | |||
| 7 | F | 79 | 6:15 | Unknown | 6 | |||
| 8 | F | 78 | 10:00 | Unknown | 5 | |||
| 9 | F | 72 | 7:15 | Heart failure | 6 | |||
| 10 | M | 74 | 10:15 | Euthanasia | 2 | |||
MS: multiple sclerosis; y: years; h: hours; m: minutes; M: male; F: female; PPMS: primary progressive multiple sclerosis; SPMS: secondary progressive multiple sclerosis.