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. 2021 Feb 15;6(9):2767–2782. doi: 10.1016/j.bioactmat.2021.02.004

Fig. 5.

Fig. 5

The cell viability and apoptosis of MDA-MB-231 cells after recellularization for 10 d. (a) Cell viability of MDA-MB-231 cells after treatment with DDP for 48 h (n = 3). (b) IC50 values of DDP for MDA-MB-231 cells. (c) Cell apoptosis of MDA-MB-231 cultured in DECM scaffolds with different stiffness after treated with 20 μM DDP for 48 h. (d) Statistical data of apoptosis (n = 3). *P < 0.05 represents statistically significant difference compared with the TCPS group. **P < 0.01 represents extremely statistically significant difference compared with the TCPS group. #P < 0.05 represents statistically significant difference compared with the Low group. ##P < 0.01 represents extremely statistically significant difference compared with the Low group. Statistical significance was determined by ANOVA followed by Tukey's post hoc test. Low: low stiffness group; Medium: medium stiffness group; High: high stiffness group.