FIGURE 2.

Levels of biochemical markers according to the presence of CINV. A and B, Leptin level according to the presence of nausea or vomiting during the 4 days after chemotherapy. C and D, Ghrelin level according to the presence of nausea or vomiting during the 4 days after chemotherapy. E and F, Substance P level according to the presence of nausea or vomiting during the 4 days after chemotherapy. Patients with nausea had higher levels of substance P on day 1 (baseline) and day 3 after chemotherapy. G and H, Changes in leptin, ghrelin, and substance P levels after chemotherapy according to the presence of nausea or vomiting on day 1 or day 2. Patients with vomiting had significantly increased leptin levels. The Mann–Whitney U‐test was used to compare continuous values