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. 2020 Dec 30;10(3):883–894. doi: 10.1002/cam4.3669

TABLE 2.

Comparisons of 3‐year survival rates among groups defined by plasma EBV DNA dynamic change patterns across 4 time points pre‐ and posttreatment

Subject N (%) PFS DMFS LRFS OS
EBV‐DNA Dynamic change pattern 252 p < 0.001 p < 0.001 p < 0.001 p < 0.001
Pattern 1 (Pre‐ & Post 0+) 82 (32.5%) 91.4% 97.5% 95.0% 96.2%
Pattern 2 (Pre+ & Post 0+) 104 (41.3%) 86.2% 92.0% 92.1% 99.0%
Pattern 3 (Pre‐ & Post 1+) 18 (7.2%) 66.7% 77.8% 88.2% 94.4%
Pattern 4 (Pre+ & Post 1+) 17 (6.7%) 39.7% 70.6% 69.5% 87.4%
Pattern 5 (Pre‐/+ & Post ≥2+) 31 (12.3%) 6.5% 17.9% 49.1% 55.3%

Abbreviations: DMFS, distant metastasis‐free survival; LRFS, locoregional relapse‐free survival; OS, overall survival; PFS, progression‐free survival.