Table 6.
Effect of Crude Extract and Solvent Fractions of Urtica simensis on Lipid Profiles
| Experimental Groups | Triglycerides | Total Cholesterol |
|---|---|---|
| Normal control (2% tween 80%) | 62.00±6.13 | 44.67±6.43 |
| Negative control CP(200mg/kg i.p) | 119.00±10.98a*** | 153.83±26.36a** |
| Positive control (EN10mg/kg/Po) | 63.17±2.07b*** | 66.17±6.67b* |
| CE(100mg/kg)+CP(200mg/kg) | 69.33±10.73b** | 118.83±27.64 |
| CE(200mg/kg)+CP(200mg/kg) | 64.17±9.29b*** | 59.50±14.12b* |
| CE(400mg/kg)+CP(200mg/kg) | 56.67±2.93b*** | 53.33±14.83b** |
| Aqueous(200mg/kg)+ CP(200mg/kg) | 74.17±10.55b*** | 70.33±8.88b* |
| Aqueous(400mg/kg)+ CP(200mg/kg) | 74.00±6.35b*** | 55.67±14.06b** |
| Hexane(200mg/kg)+ CP(200mg/kg) | 76.50±8.04b* | 82.00±14.86 |
| Hexane(400mg/kg)+ CP(200mg/kg) | 77.17±12.20b* | 79.83±24.21 |
Notes: Mean ±SEM (n= 6); analysis was performed using one way ANOVA followed by Tukey post hoc test; aCompared with normal control; bCompared with negative control (CP);*p<0.05; **p<0.01; ***p<0.001.
Abbreviations: AF, aqueous fraction; CE, crude extract; CP, cyclophosphamide; EN, enalapril; HF, hexane fraction; Wt., weight.