Fig. 4.

Alb treatment improves inflammatory and redox state in DSS colitis. (A) Effect of Alb treatment on inflammatory cytokines in the colon. Protein extracted from colon tissues on day 7 after DSS administration was measured for the level of IL-α, β, and TNF-α with ELISA. Data shown are mean ± SD (n = 4; ^##P < 0.01 vs. NC; *P < 0.05, **P < 0.01). (B–D) Effect of Alb treatment on sulfenic acid formation in colon, feces, and serum. Proteins obtained from colon tissues, feces, and serum were treated with dimedone and subjected to Western blot analysis for sulfenic acid formation. The densitometric quantification of the signals in the blots was performed and the data are presented in the bar graph at the right side of the blot (mean ± SD; n = 4; ^##P < 0.01 vs. NC; *P < 0.05, **P < 0.01).