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. 2021 Feb 22;21:58. doi: 10.1186/s12866-021-02107-3

Table 1.

The SARS-COV-2 N protein physicochemical analysis and subcellular localization

Project Name Results
Formula C1971H3137N607O629S7
Number of amino acids 419
Molecular weight 45.6 kDa
Theoretical pI 10.07
Number of charged residues
 Positively (Arg + Lys + His) 60
 Negatively (Asp + Glu) 36
Estimated half-life
 Mammalian reticulocytes 30 h (vitro)
 Yeast > 20 h (vivo)
 Escherichia coli > 10 h (vivo)
Instability index 55.09
Aliphatic index 52.53
GRAVY − 0.971
Subcellular localization (KNN)
 Nuclear 69.6%
 Cytoplasmic 21.7%
 Cytoskeletal 4.3%
 Vesicles of secretory system 4.3%