Table 4.
Sites | Deletion | Insertion | Replacements | ||||||
---|---|---|---|---|---|---|---|---|---|
Variant | score | Prediction | Variant | score | Prediction | Variant | score | Prediction | |
49 T | T49_S51del | −4.946 | Da | T49_S51dup | −1.515 | N | T49delinsSW | −3.009 | D |
232S | S232_M234del | −1.561 | N | S232_M234dup | −1.573 | N | S232delinsMS | −1.350 | N |
245 T | T245_T247del | −5.955 | D | T245_T247dup | −3.081 | D | T245delinsTK | −0.686 | N |
366 T | T366_P368del | −3.160 | D | T366_P368dup | −0.983 | N | T366delinsPK | −0.985 | N |
379 T | T379_A381del | −1.021 | N | T379_A381dup | 0.060 | N | T379delinsAL | −1.584 | N |
391 T | T391_T393del | −0.007 | N | T391_T393dup | −0.175 | N | T391delinsTL | −1.299 | N |
393 T | T393_L395del | 0.779 | N | T393_L395dup | −1.736 | N | T393delinsLP | −1.429 | N |
413S | S413_D415del | −1.187 | N | S413_D415dup | 1.058 | N | S413delinsDS | 1.891 | N |
417 T | T417_A419del | 0.182 | N | T417_A419dup | 0.488 | N | T417delinsAA | 0.420 | N |
aDefault threshold is − 2.5, that is: Variants with a score equal to or below − 2.5 are considered “Deleterious”; Variants with a score above − 2.5 are considered “Neutral”