Figure 2.

Liver-specific deletion of Atg7 caused gut dysbiosis. Shannon species diversity (A) and the number of species identified (B) were analyzed in each group of mice. (C) Bacteria with disproportionate representation in Atg7^Δhep mice at genus level. Heatmap was generated, and values in the heatmap were mapped to colors using the minimum and maximum of each row independently. The hierarchical cluster of different genus was constructed using one minus Pearson correlation method. Male and female mice were 6–26 weeks old when fecal samples were collected (n = 5). Data are shown as median with interquartile range. Mann-Whitney analysis did not show statistical significance between the groups.