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ABX treatment suppressed ileal FXR activity and altered enterohepatic TBA levels in Atg7Δhepmice. (A) TBA levels in the indicated compartments were measured (n = 4–6). (B) Serum levels of ALT, AST, ALP, and TBA in Atg7Δhep mice after ABX treatment (n = 4–6). (C) Liver weight and gallbladder (Gal) weight were shown as percentage of body weight (n = 4–6). Data are shown as means ± SE. Groups with different lowercase letters had significant differences (P < .05).
