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Alterations in the proportion of BA-metabolizing bacteria in Atg7Δhepmice. (A) Proportion of bacteria with BSH and/or 7α/β-dehydroxylation activity at the genus level in floxed Atg7 or in Atg7Δhep mice. Mice were 6–26 weeks old. Both male and female mice were included. (B) The bacterial species with BSH and/or 7α/β-dehydroxylation activity that were disproportionate in Atg7Δhep mice. Data are shown as median with interquartile range, n = 5. Mann-Whitney analysis, ∗P < .05, ∗∗P < .01.
