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. 2021 Feb 8;12:601404. doi: 10.3389/fphar.2021.601404

FIGURE 2.

FIGURE 2

Effects of δ-opioid receptor agonist (SNC-121) treatment on interleukin-1β (IL-1β) (A) and interleukin-6 (IL-6) (B) production in ocular hypertensive animal. Animals were euthanized and eyes were enucleated at day 7, post hypertonic saline injections. Retina cryosections were immunostained using a selective anti-IL-1β or anti-IL-6 antibody. The nuclei were counterstained with DAPI. Red color indicates staining for IL-1β and IL-6 and blue for the nuclei. There was no positive immunostaining when primary antibodies were omitted (not shown). Data shown here is a representation of at least four independent experiments. We have used four animals in each treatment group. OH Eyes; ocular hypertensive eyes; OH Eyes + SNC-121, ocular hypertensive eyes with SNC-121 treatment, bar size 20 µm.

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