TABLE 2.

Cox regression analysis of factors associated with prolonged severe acute respiratory syndrome coronavirus 2 positivity

	Univariate analysis		Multivariate analysis
	p-value	HR (95% CI)	p-value	HR (95% CI)
Age	0.335	1.013 (0.987–1.041)	0.831	0.995 (0.954–1.03)
Sex (male=1, female=2)	0.415	1.395 (0.627–3.102)	0.077	2.531 (0.905–7.073)
Disease severity (severe=1, nonsevere=0)	0.075	1.894 (0.939–3.824)	0.025*	3.260 (1.162–9.147)
Oxygen insufflation necessary (yes=1, no=0)	0.573	1.321 (0.502–3.473)	0.057	3.960 (0.961–16.319)
Hydroxychloroquine therapy (yes=1, no=0)	0.082	0.490 (0.219–1.095)	0.263	0.597 (0.242–1.474)
Lopinavir/ritonavir treatment (yes=1, no=0)	0.796	1.149 (0.401–3.296)	0.384	1.713 (0.509–5.765)
Immunosuppressive treatment (tocilizumab/prednisolone/others; yes=1, no=0)	0.233	1.723 (0.704–4.215)	0.110	2.748 (0.794–9.511)
Diabetes mellitus (yes=1, no=0)	0.953	0.975 (0.422–2.254)	0.704	1.243 (0.404–3.825)
Arterial hypertension (yes=1, no=0)	0.621	1.193 (0.593–2.401)	0.572	0.765 (0.302–1.939)
Coronary artery disease (yes=1, no=0)	0.787	1.141 (0.440–2.959)	0.968	0.978 (0.326–2.930)
Charlson Comorbidity Index (0–7)	0.425	1.082 (0.891–1.314)	0.850	1.036 (0.719–1.493)

HR: hazard ratio. *: p<0.05.