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. 2021 Feb 17;14:413–428. doi: 10.2147/JIR.S297081

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© 2021 Luo et al.

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Protein-protein interaction (PPI) network of differentially expressed mRNAs (A) and the top three clusters (B–D) of PPIs. (A) The PPI network consists of 282 nodes and 307 edges. Dot size represents the MCC of nodes. (B–D) The top three highly MCC connected clusters are composed of nine hub genes, six hub genes, and eleven hub genes.

Abbreviations: PPI, protein-protein interaction network; MCC, maximal clique centrality.