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. 2020 Dec 29;73(2):203–211. doi: 10.1002/art.41517

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© 2020 The Authors. Arthritis & Rheumatology published by Wiley Periodicals LLC on behalf of American College of Rheumatology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Local genetic correlation between obesity‐related traits and rheumatoid arthritis (RA). Plots show region‐specific P values for the local genetic covariance between RA and body mass index (BMI), waist‐to‐hip ratio (WHR), and WHR adjusted for BMI (WHRadjBMI) overall (both) and in female and male subjects analyzed separately. Each dot presents a specific genomic region. Red indicates significance after multiple corrections (P < 3 × 10⁻⁵ [0.05/1,703 regions compared]); blue indicates nominal significance under an arbitrary threshold of P < 5 × 10⁻⁵.