Figure 3.

The photonumeric scale was applied in a split‐face randomized clinical trial to evaluate the efficacy of a cosmetic treatment product. (A) Clinical scoring of dark circles in both the treated and untreated under‐eye area over 8 weeks (n = 58). (B) Mean grade changes from baseline and net difference in grade treated versus untreated. Improvements were statistically significant (P < 0.001, Wilcoxon signed rank test) between post‐baseline grades and baseline grades and between the treated and untreated sites at all post‐baseline time point.