FIGURE 4.

YAP/TAZ‐null animal display diminished functional recovery. (a,b) Measurements of compound muscle action potential (CMAP) of control and Yap ^cHet; Taz ^cKO animals from contralateral control and side of nerve crush at 20 and 60 days after nerve crush injury. (c,d) Measurements of nerve conduction velocity (NCV) of control and Yap ^cHet; Taz ^cKO animals from contralateral control and side of nerve crush at 20 and 60 days after nerve injury. (e,f) Measurements of grip strength of control and Yap ^cHet; Taz ^cKO animals from contralateral control and side of nerve crush at 20 and 60 days after nerve injury. Grip strength measurement were normalized to the weight of the mice. (g–i) Mechanical threshold measurements of control and Yap ^cHet; Taz ^cKO animals from contralateral and nerve crush side at 20 and 60 days after nerve injury (g,h). Mechanical threshold in uninjured control and Yap ^cHet; Taz ^cKO animals at 60 days of age (i). n ≥ 4 mice for each genotype and time point. Data are presented as means ± SEM. Two‐sided Student's t test: ****, p ≤ 0.0001; ***, p ≤ 0.001; **, p ≤ .01 [Color figure can be viewed at wileyonlinelibrary.com]